Apoptosis Reagents and Kits
Cayman Chemical Z-VAD OH-FMK 500ug
An irreversible tripeptide inhibitor of all caspases; useful in studies involving recombinant, isolated, or purified enzymes
Biolegend PE Annexin V Reactivity: All mammalian species; Apps: FC; Size: 100 tests
PE Annexin V Reactivity: All mammalian species; Apps: FC; Size: 100 tests
Biotium Apoptotic, Necrotic & Healthy Cells Quantification Kit (50 assays)
This kit provides a convenient assay for quantifying apoptotic (green) and necrotic (red) cells within the same cell population by flow cytometry or fluorescence microscopy. The kit contains FITC-Annexin V which binds to apoptotic cells by binding to phosphatidylserine (PS) exposed on the cell surface, and Ethidium Homodimer III (EthD-III) which is a membrane impermeant nucleic acid probe specific for dead cells. Staining is rapid, requiring only a single 15-30 minute staining step. FITC-Annexin V has an excitation emission of 498/517 nm, and EthD-III has an excitation/emission of 522/593 nm (and a large absorption peak at 279 nm) when bound to DNA. The kit also contains a membrane permeable DNA dye Hocechst 3342 to stain all cell nuclei blue for analysis of healthy cells. The kit has reagents sufficient reagent for 50 assays.
Biotium Annexin V, CF350 Conjugate
Annexin V fluorescent conjugates can be used to detect apoptotic cells. The human anticoagulant Annexin V is a 35-36 kDa calcium-dependent phospholipid-binding protein with high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the inner leaflet of the cytoplasmic membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasma membrane, where it can be detected by fluorescently labeled Annexin V. CF Dye Annexin V Conjugates are provided at 50 ug/mL in buffer with azide as a preservative. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. UV-excitable blue fluorescent CF350 dye has excitation/emission at 347/448 nm.
Biotium Annexin V, Biotin Conjugate
Annexin V fluorescent conjugates can be used to detect apoptotic cells. The human anticoagulant Annexin V is a 35-36 kDa calcium-dependent phospholipid-binding protein with high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the inner leaflet of the cytoplasmic membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasma membrane, where it can be detected by fluorescently labeled Annexin V. Biotin Annexin V conjugate is provided at 50 ug/mL in buffer with azide as a preservative.
Biotium CF640R TUNEL Assay Apoptosis Detection Kit
In the TUNEL assay, TdT enzyme catalyzes the addition of labeled dUTP to the 3'- ends of the internucleosomal DNA strand breaks that are a hallmark of apoptosis. The CF dye TUNEL Assay Apoptosis Detection Kit employs dUTP conjugated to Biotium's exceptionally bright and photostable CF fluorescent dyes, for single step fluorescent TUNEL labeling of fixed cells or tissues for analysis by fluorescence microscopy or flow cytometry. This kit contains CF640R which has an excitation/emission of 642/662 nm. The kit has reagents sufficient for 50 reactions.
Biolegend Pacific Blue™ Annexin V
Pacific Blue™ Annexin V Reactivity: All mammalian species; Apps: FC; Size: 25 tests
Cayman Chemical Z-VAD OH-FMK 1mg
An irreversible tripeptide inhibitor of all caspases; useful in studies involving recombinant, isolated, or purified enzymes
Enzo Life Sciences BAFF-R (human) : Fc (human), (recombinant) (50µg)
Alternative name: TNFRSF 13C, BR3, BlySR3, CD268. Concentration: 1mg/ml (after reconstitution). Purity: ≥95% (SDS-PAGE). Formulation: Lyophilized. Contains PBS. Source: Produced in HEK 293 cells. The extracellular domain of human BAFF-R (aa 2-71) is fused at the C-terminus to the Fc portion of human IgG1. Specificity: Binds human and mouse BAFF. Long Term Storage: -20°C. Applications: ELISA .
Immunology Consultants anti-Hamster (CHO) Annexin A5 Antibody - Affinity Purified
This affinity‑purified chicken antibody targets hamster (CHO) Annexin A5, a calcium‑dependent phospholipid‑binding protein associated with membrane dynamics, apoptosis signaling, and cellular stress responses. Designed for high‑specificity detection in CHO‑based systems, it performs reliably in ELISA, Western blotting, and impurity profiling workflows. The avian origin reduces interference from mammalian immunoglobulins, supporting low‑background, high‑signal assays even in complex matrices. Its rigorous purification ensures strong affinity and reproducible performance, making it a valuable reagent for bioprocess development, HCP monitoring, and analytical characterization of CHO‑derived proteins involved in membrane stability and cell viability.
Selleck Chemical LLC GSK2656157 50mg 1337532-29-2
GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM in a cell-free assay, 500-fold greater against a panel of 300 kinases. GSK2656157 decreases apoptosis and inhibits excessive autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical Z-YVAD-CMKtrIfluoroacetate 1mg
An inhibitor of caspase-1 and caspase-3; reduces IL-1β and IL-18 secretion in isolated mouse peritoneal macrophages by cholesterol-treated rPLY at 30 µM; reduces caspase-3 activation by the EGF-like domain of tenascin-C in detached hSMCs in vitro; decreases cell death induced by the EGF-like domain of tenascin-C by 50% at 100 µM; completely inhibits cell death of hSMCs at 200-400 µM